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Obesity-related chronic conditions like type 2 and kidney disease are among the top culprits of this disparity ( source )

So were going to need a combination of different kinds of evidence

Walking, strength training, or other manageable activities support your metabolism and help maintain muscle as the drugs assist with weight control

Side effects become more predictable

Overeating can increase feelings of nausea, bloating, acid reflux, and fullness

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